Dr Akefe Isaac is an expert biomedical researcher focusing on basic cellular mechanisms and/or pathways involved in the development and progression of oxidative stress in memory impairment, and disease-related pathology. His research also focuses on finding alternative antioxidant therapy for the amelioration of oxidative stress and enhancement of memory. He is an expert in cell and animal model (rodent species) studies, used in medical research to investigate disease mechanisms and novel drug discovery. Akefe’s skills in tissue culture, flow cytometry, polymerase chain reaction, histology, liquid chromatography, and mass spectrometry, gained by training during his postgraduate research study is useful for disease diagnosis and helpful to clinicians in patient’s care. Akefe is currently a lecturer at the Faculty of Veterinary Medicine, University of Jos Nigeria, with several active ongoing research collaborations internationally, including Egypt, India, Saudi Arabia, Australia, Nigeria, and the USA.
Selected Publications
1. Akefe, I., Ayo, J., & Sinkalu, V. (2021). Assortment of kaempferol and zinc gluconate improves noise-induced biochemical imbalance and deficits in body weight gain. Experimental Results 1-21. doi:10.1017/exp.2021.30, (Cambridge core).
2. Akefe IO, Ayo JO, Sinkalu VO (2020) Kaempferol and zinc gluconate mitigate neurobehavioral deficits and oxidative stress induced by noise exposure in Wistar rats. PLOS ONE 15(7): e0236251. https://doi.org/10.1371/journal.pone.0236251.
3. Akefe IO, Yusuf IL, Adegoke VA (2019). C-glycosyl flavonoid orientin alleviates learning and memory impairment by radiofrequency electromagnetic radiation in mice via improving antioxidant defence mechanism. Asian Pac J Trop Biomed, 9:518523. doi.org/10.4103/2221-1691.271725.